Patient Medication Guide

Coumadin

What is warfarin (Coumadin), and how does it work?

Warfarin is a prescription medicine that helps stop abnormal blood clots from forming or growing larger in blood vessels. Because clots can block blood flow, they can cause a heart attack, brain attack (stroke), and other serious problems.

Prescription Anticoagulant Helps prevent and treat blood clots
PT/INR Monitoring Regular blood testing is essential
Take Exactly as Directed Never double or change a dose yourself

Safe treatment depends on consistent monitoring

Your dose and testing schedule are individualized by your healthcare provider.

01 · Regular Testing

Blood testing is essential

While taking warfarin, you must have regular blood tests to make sure you are receiving enough warfarin to stop harmful clots—but not so much that your blood cannot clot when it should, such as after a cut.

02 · Take as Directed

How do I take warfarin?

Because warfarin increases your risk for bleeding, take it exactly as your healthcare provider tells you.

03 · Monitoring

PT/INR blood tests

PT/INR stands for prothrombin time and international normalized ratio. Your healthcare provider will decide how often you need testing—commonly every one to four weeks—and may change your warfarin dose based on the results.

04 · The Goal

Balance clotting and bleeding risk

An INR below your personal target may increase the risk of a harmful clot, while an INR above your target may increase the risk of bleeding. Follow the target range given by your healthcare provider.

Follow these instructions while taking warfarin

Consistency and communication with every member of your healthcare team are essential.

Take warfarin at the same time each day.
If you miss or forget a dose, call your healthcare provider for advice. Do not take a double dose.
Warfarin generally should not be used during pregnancy. If you are pregnant, may become pregnant or plan to breastfeed, contact your healthcare provider promptly for individualized instructions. Do not stop or change the medication on your own.
Tell all healthcare providers, including your dentist, that you take warfarin. Before surgery, medical tests or dental procedures, your healthcare provider will tell you whether warfarin needs to be temporarily stopped.
Talk to your healthcare provider before taking any new prescription or over-the-counter medicine, herbal supplement or vitamin.
Call your healthcare provider immediately for unusual bleeding or bruising, including bleeding that will not stop, bleeding gums, pink or brown urine, red or dark stool, unusually heavy menstrual or vaginal bleeding, nosebleeds, or coughing up or vomiting blood or material that looks like coffee grounds.

Know when to seek immediate help

Call your healthcare provider immediately—or call 911 when symptoms are severe, sudden or life-threatening—if you have a severe headache, worsening fever or illness, dizziness or weakness, chest pain, trouble breathing, or new pain or changes in color or temperature in any part of your body, such as your toes.

If you hit your head, seek emergency medical evaluation right away to make sure there is no bleeding in the brain, even if you initially feel well.

For bleeding that will not stop or another medical emergency, call 911.

Diet and bleeding precautions

Small, consistent habits can help your treatment work safely.

Diet & Vitamin K

Do I have to change my diet?

Eat a normal, balanced diet. Do not make dietary changes without first talking to your healthcare provider.

Foods rich in vitamin K—especially dark green or leafy vegetables such as broccoli and spinach—can change warfarin’s effect. You do not have to avoid these foods, but try to keep the amount you eat consistent from week to week.

Do not drink alcohol. Avoid cranberry juice and cranberry products because they can affect how warfarin works in your body.

Preventing Injury

How can I reduce bleeding risk?

Because you may bleed more easily, take these precautions:

  • Clean your teeth gently with a soft-bristle toothbrush and waxed floss.
  • Use an electric razor or hair-removal cream instead of a razor blade.
  • Take care not to cut yourself when using knives and other sharp objects.
  • Do not walk barefoot, and avoid activities with a risk of injury, such as contact sports.
If bleeding starts, apply constant pressure. If it does not stop within 10 minutes, call your healthcare provider or 911 for help.
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